Melioidosis

2005, Mark A. Suckov, Alexander Valisenko, Nikolai Tokarevich, Chapter 3: Animals Models in Biodefense Research, Jann Hau, Steven J. Schapiro, Gerald L. Van Hoosier, Jr. (editors), Handbook of Laboratory Animal Science, Volume 3: Animal Models, 2nd Edition, 40, A close relative of the agent of glanders, B. pseudomallei causes a disease (melioidosis) with clinical manifestations including asymptomatic pneumonitis, acute or chronic pneumonia, and overwhelming septicemia.

Twenty-seven proteins distinctively reacted with human plasma following environmental exposure or clinical melioidosis.

Melioidosis is the etiological designation of a spectrum of clinical manifestations caused by the gram-negative bacillus Burkholderia pseudomallei.

Burkholderia pseudomallei is the cause of meliodosis, which is a multiorgan infection seen mainly in South East Asia and Northern Australia. Meliodosis often first presents with lung disease, which may be an acute pneumonia or more chronic lung disease, sometimes resembling TB.